How Weight Loss Medication Works

From your first consultation to ongoing treatment — the full process of GLP-1 weight loss injections explained.

What Are GLP-1 Weight Loss Injections?

GLP-1 receptor agonists (such as Mounjaro, Wegovy, and Saxenda) are a class of prescription medication originally developed for type 2 diabetes that have been shown to produce significant weight loss in clinical trials.

They work by mimicking a natural hormone called glucagon-like peptide-1 (GLP-1), which is released by your gut after eating. This hormone:

  • Signals to your brain that you are full, reducing appetite
  • Slows the rate at which food leaves your stomach (gastric emptying)
  • Helps regulate blood sugar levels after meals
  • Mounjaro also activates the GIP receptor for enhanced effects

All three medications are approved by NICE for weight management in adults who meet the eligibility criteria (typically a BMI of 30+, or 27+ with comorbidities).

The Process: 5 Steps

From choosing a provider to ongoing treatment — here is what to expect.

1. Research & Compare

Use WhichWeightMeds.org to compare verified UK providers. Check prices, medication availability, delivery options, and Trustpilot reviews.

2. Online Consultation

Complete a medical questionnaire with your chosen provider. A UK-registered prescriber reviews your health history, BMI, and suitability for treatment.

3. Medication Delivered

If approved, your medication is dispensed by a GPhC-registered pharmacy and delivered to your door in temperature-controlled packaging.

4. Start Treatment

Begin with a low starter dose and inject as directed. Your provider will guide you through the titration schedule, gradually increasing the dose.

5. Ongoing Support & Reorders

Attend follow-up consultations, track your progress, and reorder medication as needed. Most providers offer subscription plans for convenience.

Ready to Start?

Compare verified UK providers and find the right weight loss medication for you.