How Weight Loss Medication Works
From your first consultation to ongoing treatment — the full process of GLP-1 weight loss injections explained.
What Are GLP-1 Weight Loss Injections?
GLP-1 receptor agonists (such as Mounjaro, Wegovy, and Saxenda) are a class of prescription medication originally developed for type 2 diabetes that have been shown to produce significant weight loss in clinical trials.
They work by mimicking a natural hormone called glucagon-like peptide-1 (GLP-1), which is released by your gut after eating. This hormone:
- Signals to your brain that you are full, reducing appetite
- Slows the rate at which food leaves your stomach (gastric emptying)
- Helps regulate blood sugar levels after meals
- Mounjaro also activates the GIP receptor for enhanced effects
All three medications are approved by NICE for weight management in adults who meet the eligibility criteria (typically a BMI of 30+, or 27+ with comorbidities).
The Process: 5 Steps
From choosing a provider to ongoing treatment — here is what to expect.
1. Research & Compare
Use WhichWeightMeds.org to compare verified UK providers. Check prices, medication availability, delivery options, and Trustpilot reviews.
2. Online Consultation
Complete a medical questionnaire with your chosen provider. A UK-registered prescriber reviews your health history, BMI, and suitability for treatment.
3. Medication Delivered
If approved, your medication is dispensed by a GPhC-registered pharmacy and delivered to your door in temperature-controlled packaging.
4. Start Treatment
Begin with a low starter dose and inject as directed. Your provider will guide you through the titration schedule, gradually increasing the dose.
5. Ongoing Support & Reorders
Attend follow-up consultations, track your progress, and reorder medication as needed. Most providers offer subscription plans for convenience.