Frequently Asked Questions

Based on clinical trial data, Mounjaro (tirzepatide) has shown the greatest average weight loss at 22.5% of body weight over 72 weeks (SURMOUNT-1 trial, NEJM 2022). Wegovy showed 14.9% over 68 weeks, while Saxenda showed 8.0% over 56 weeks.

Both are weekly injections, but they work differently. Mounjaro targets two hormone receptors (GIP and GLP-1), while Wegovy targets only GLP-1. In clinical trials, Mounjaro produced greater average weight loss (22.5% vs 14.9%). Both are NICE-approved for weight management.

Weight loss medications are typically used on an ongoing basis. NICE guidance notes that weight regain commonly occurs after stopping treatment. Your prescriber will discuss the appropriate duration based on your circumstances.

There is no absolute ban on alcohol, but GLP-1 medications can affect blood sugar levels and increase the risk of nausea. Most prescribers advise moderation. Speak to your prescriber for personalised advice.

Generally, weight loss medications are prescribed for adults aged 18+ with a BMI of 30 or above, or a BMI of 27+ with at least one weight-related condition. You will need to complete a medical consultation.

Both are NICE-approved for NHS use within specialist weight management services, but real-world availability varies significantly by region. Many patients access these medications privately.

No. You can access weight loss medications privately without a GP referral by completing an online consultation with a registered prescriber.

The most common side effects are nausea, diarrhoea, constipation, and vomiting. These are usually mild to moderate and tend to improve as your body adjusts over the first few weeks.

GLP-1 medications have been studied in large clinical trials and are approved by the MHRA and NICE. However, they carry risks including pancreatitis. Always use under medical supervision.

Contact your prescriber, GP, or call NHS 111. For serious symptoms such as severe abdominal pain, allergic reactions, or thoughts of self-harm, seek immediate medical attention or call 999.

Prices vary by provider and medication. Starting prices are typically: Mounjaro from £149/month, Wegovy from £155/month, and Saxenda from £155/month. Higher doses cost more.

Every provider is checked against the GPhC register. We verify their registration status, pharmacy number, and that they are authorised to dispense prescription medications.

Yes. You are not locked into any provider. A new provider will ask about your current dose and treatment history. See our guide on switching providers.